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"Molekularbiologie der Zelle" ist das führende Lehrbuch der Zellbiologie, international ebenso wie im gesamten deutschsprachigen Raum. Studierende in den Fächern Molekularbiologie, Genetik, Zellbiologie, Biochemie und Biotechnologie begleitet dieses Buch durch das gesamte Studium, die Prüfungen und darüber hinaus. Mit erstklassiger und bewährter Didaktik führt die sechste Auflage sowohl in die grundlegenden Konzepte der Zellbiologie als auch in deren faszinierende Anwendungen in Medizin, Gentechnik und Biotechnologie ein. Sie vermittelt neue Erkenntnisse zu intrazellulärer Organisation, Membranstruktur, Dynamik und Transport und stellt hochaktuelle Themen verständlich dar, wie Nuclear Reprogramming und neu entdeckte Funktionen der RNA. Der unverwechselbare, zum Lesen verführende «Alberts»-Stil wird ergänzt durch über 1400 Farbabbildungen und 21 große Tafeln, die komplexe Vorgänge, klassische Experimente und aktuelle Methoden verdeutlichen. Vertieft wird der Stoff durch das frei zugängliche Zusatzmaterial auf www.wiley-vch.de/home/MolBioZelle6. Kostenloses Bonusmaterial für Dozenten ist erhältlich auf www.wiley-vch.de/textbooks.

This book is a welcome introduction and reference for users and innovators in geochronology. It provides modern perspectives on the current state-of-the art in most of the principal areas of geochronology and thermochronology, while recognizing that they are changing at a fast pace. It emphasizes fundamentals and systematics, historical perspective, analytical methods, data interpretation, and some applications chosen from the literature. This book complements existing coverage by expanding on those parts of isotope geochemistry that are concerned with dates and rates and insights into Earth and planetary science that come from temporal perspectives. Geochronology and Thermochronology offers chapters covering: Foundations of Radioisotopic Dating; Analytical Methods; Interpretational Approaches: Making Sense of Data; Diffusion and Thermochronologic Interpretations; Rb-Sr, Sm-Nd, Lu-Hf; Re-Os and Pt-Os; U-Th-Pb Geochronology and Thermochronology; The K-Ar and 40Ar/39Ar Systems; Radiation-damage Methods of Geo- and Thermochronology; The (U-Th)/He System; Uranium-series Geochronology; Cosmogenic Nuclides; and Extinct Radionuclide Chronology. Offers a foundation for understanding each of the methods and for illuminating directions that will be important in the near future Presents the fundamentals, perspectives, and opportunities in modern geochronology in a way that inspires further innovation, creative technique development, and applications Provides references to rapidly evolving topics that will enable readers to pursue future developments Geochronology and Thermochronology is designed for graduate and upper-level undergraduate students with a solid background in mathematics, geochemistry, and geology.

Two major challenges to continued global food security are the ever increasing demand for food products, and the unprecedented abiotic stresses that crops face due to climate change.Wild relatives of domesticated crops serve as a reservoir of genetic material, with the potential to be used to develop new, improved varieties of crops. Crop Wild Relative and Climate Change integrates crop evolution, breeding technologies and biotechnologies, improved practices and sustainable approaches while exploring the role wild relatives could play in increasing agricultural output. Crop Wild Relative and Climate Change begins with overviews of the impacts of climate change on growing environments and the challenges that agricultural production face in coming years and decades. Chapters then explore crop evolution and the potential for crop wild relatives to contribute novel genetic resources to the breeding of more resilient and productive crops. Breeding technologies and biotechnological advances that are being used to incorporate key genetic traits of wild relatives into crop varieties are also covered. There is also a valuable discussion on the importance of conserving genetic resources to ensure continued successful crop production. A timely resource, Crop Wild Relative and Climate Change will be an invaluable resource for the crop science community for years to come.

Biomedical Devices: Design, Prototyping, and Manufacturing features fundamental discussions of all facets of materials processing and manufacturing processes across a wide range of medical devices and artificial tissues. Represents the first compilation of information on the design, prototyping, and manufacture of medical devices into one volume Offers in-depth coverage of medical devices, beginning with an introductory overview through to the design, manufacture, and applications Features examples of a variety of medical applications of devices, including biopsy micro forceps, micro-needle arrays, wrist implants, spinal spacers, and fixtures Provides students, doctors, scientists, and technicians interested in the development and applications of medical devices the ideal reference source

As pressures on Australia’s inland waters intensify from population growth, expanding resource development and climate change, there is an urgent need to manage and protect these special areas. Understanding their ecology underpins their wise management and conservation. Australian Freshwater Ecology vividly describes the physical, chemical and biological features of wetlands, lakes, streams, rivers and groundwaters in Australia. It presents the principles of aquatic ecology linked to practical management and conservation, and explains the causes, mechanisms, effects and management of serious environmental problems such as altered water regimes, eutrophication, salinization, acidification and sedimentation of inland waters. Key features: contributions from a diverse, highly qualified team of aquatic ecologists whose expertise spans the ecology and management of standing and running waters in Australia sections covering groundwaters, biodiversity, temporary and tropical waters, climate change, invasive species and freshwater conservation numerous Australian case-studies and guest ‘text-boxes’ showing management in practice concise descriptions of ecological processes and conceptual models illustrated with original, high- quality diagrams and photographs Readable and logically structured, this text supports undergraduate and postgraduate courses in aquatic ecology and management. It is a valuable reference for consultants, restoration ecologists, water resource managers, science teachers, and other professionals with an interest in the ecology of surface and groundwaters.

An international group of distinguished scholars pay homage to and build on the work of one of the most influential thinkers of our time, Michael Watts. Shows how Michael Watts’ research, writings, teaching and mentoring have relentlessly pushed boundaries, transforming his chosen field of geography and beyond Spans an array of topics including the political economy and ecology of African societies, governmentality and territoriality in various Southern contexts, food security, cultural materialist expositions of capitalism, modernity and development across the postcolonial world Builds on his legacy, exploring its theoretical, analytical, and empirical implications and proposing exciting new possibilities for further exploration in the tracks of Watts

Subduction dynamics has been actively studied through seismology, mineral physics, and laboratory and numerical experiments. Understanding the dynamics of the subducting slab is critical to a better understanding of the primary societally relevant natural hazards emerging from our planetary interior, the megathrust earthquakes and consequent tsunamis. Subduction Dynamics is the result of a meeting that was held between August 19 and 22, 2012 on Jeju island, South Korea, where about fifty researchers from East Asia, North America and Europe met. Chapters treat diverse topics ranging from the response of the ionosphere to earthquake and tsunamis, to the origin of mid-continental volcanism thousands kilometers distant from the subduction zone, from the mysterious deep earthquakes triggered in the interior of the descending slabs, to the detailed pattern of accretionary wedges in convergent zones, from the induced mantle flow in the deep mantle, to the nature of the paradigms of earthquake occurrence, showing that all of them ultimately are due to the subduction process. Volume highlights include: Multidisciplinary research involving geology, mineral physics, geophysics and geodynamics Extremely large-scale numerical models with sliate-of-the art high performance computing facilities Overview of exceptional three-dimensional dynamic representation of the evolution of the Earth interiors and of the earthquake and subsequent tsunami dynamics Global risk assessment strategies in predicting natural disasters This volume is a valuable contribution in earth and environmental sciences that will assist with understanding the mechanisms behind plate tectonics and predicting and mitigating future natural hazards like earthquakes, volcanoes and tsunamis.

For the 6th Edition of this highly regarded textbook devoted to lipids, the title has been modified from Lipid Biochemistry to Lipids to acknowledge the coming together of biological and medical sciences, the increasingly blurred boundaries between them and the growing importance of lipids in diverse aspects of science and technology. The principal aims of this new edition – to inform students and researchers about lipids, to assist teachers and encourage further research – have not changed since previous editions. Significant advances in lipid science have demanded yet another extensive rewriting for this edition, with the addition of two new authors, to cover new knowledge of genes coding for proteins involved in lipid metabolism, the many lipids involved in cell signalling, the roles of lipids in health and disease and new developments in biotechnology in support of agriculture and industry. An introductory chapter summarizes the types of lipids covered and their identification and provides a guide to the contents. Chapters contain boxes illustrating special topics, key point summaries and suggested further reading. Lipids: Sixth Edition provides a huge wealth of information for upper-level students of biological and clinical sciences, food science and nutrition, and for professionals working in academic and industrial research. Libraries in all universities and research establishments where biological, medical and food and nutritional sciences are studied and taught should have copies of this excellent and comprehensive new edition on their shelves.

The first book to aid in the understanding of multiconfigurational quantum chemistry, Multiconfigurational Quantum Chemistry demystifies a subject that has historically been considered difficult to learn. Accessible to any reader with a background in quantum mechanics and quantum chemistry, the book contains illustrative examples showing how these methods can be used in various areas of chemistry, such as chemical reactions in ground and excited states, transition metal and other heavy element systems. The authors detail the drawbacks and limitations of DFT and coupled-cluster based methods and offer alternative, wavefunction-based methods more suitable for smaller molecules.

Earth is the only planet known to have fire. The reason is both simple and profound: fire exists because Earth is the only planet to possess life as we know it. Fire is an expression of life on Earth and an index of life’s history. Few processes are as integral, unique, or ancient. Fire on Earth puts fire in its rightful place as an integral part of the study of geology, biology, human history, physics, and global chemistry. Fire is ubiquitous in various forms throughout Earth, and belongs as part of formal inquiries about our world. In recent years fire literature has multiplied exponentially; dedicated journals exist and half a dozen international conferences are held annually. A host of formal sciences, or programs announcing interdisciplinary intentions, are willing to consider fire. Wildfire also appears routinely in media reporting. This full-colour text, containing over 250 illustrations of fire in all contexts, is designed to provide a synthesis of contemporary thinking; bringing together the most powerful concepts and disciplinary voices to examine, in an international setting, why planetary fire exists, how it works, and why it looks the way it does today. Students, lecturers, researchers and professionals interested in the physical, ecological and historical characteristics of fire will find this book, and accompanying web-based material, essential reading for undergraduate and postgraduate courses in all related disciplines, for general interest and for providing an interdisciplinary foundation for further study. A comprehensive approach to the history, behaviour and ecological effects of fire on earth Timely introduction to this important subject, with relevance for global climate change, biodiversity loss and the evolution of human culture. Provides a foundation for the interdisciplinary field of Fire Research Authored by an international team of leading experts in the field Associated website provides additional resources

Microstructural Geochronology Geochronology techniques enable the study of geological evolution and environmental change over time. This volume integrates two aspects of geochronology: one based on classical methods of orientation and spatial patterns, and the other on ratios of radioactive isotopes and their decay products. The chapters illustrate how material science techniques are taking this field to the atomic scale, enabling us to image the chemical and structural record of mineral lattice growth and deformation, and sometimes the patterns of radioactive parent and daughter atoms themselves, to generate a microstructural geochronology from some of the most resilient materials in the solar system. First compilation of research focusing on the crystal structure, material properties, and chemical zoning of the geochronology mineral archive down to nanoscale Novel comparisons of mineral time archives from different rocky planets and asteroids and their shock metamorphic histories Fundamentals on how to reconstruct and date radiogenic isotope distributions using atom probe tomography Microstructural Geochronology will be a valuable resource for graduate students, academics, and researchers in the fields of petrology, geochronology, mineralogy, geochemistry, planetary geology, astrobiology, chemistry, and material science. It will also appeal to philosophers and historians of science from other disciplines.

Edited by a team of highly respected researchers combining their expertise in chemistry, physics, and medicine, this book focuses on the use of ruthenium-containing complexes in artificial photosynthesis and medicine. Following a brief introduction to the basic coordination chemistry of ruthenium-containing complexes and their synthesis, as well as their photophysical and photochemical properties, the authors discuss in detail the major concepts of artificial photosynthesis and mechanisms of hydrogen production and water oxidation with ruthenium. The second part of the text covers biological properties and important medical applications of ruthenium-containing complexes as therapeutic agents or in diagnostic imaging. Aimed at stimulating research in this active field, this is an invaluable information source for researchers in academia, health research institutes, and governmental departments working in the field of organometallic chemistry, green and sustainable chemistry as well as medicine/drug discovery, while equally serving as a useful reference also for scientists in industry.